This book is a continuation of the volumes providing various perspectives on computational intelligence in healthcare [1-3]. This book is aimed to provide a sample of the state of art in the practical applications of computational intelligence paradigms in healthcare. It includes nineteen chapters on using various computational intelligent paradigms in healthcare such as intelligent agents and case-based reasoning. A number of applications and case studies are presented. This book is targeted towards scientists, application engineers, professors, health professionals, professors and students.