Together with the companion volume LNCS 2489 this book constitutes the refereed proceedings of the 5th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2002, held in Tokyo, Japan, in September 2002. The 184 revised full papers presented were carefully reviewed and selected from 321 submissions. The two-volume proceedings offers main topical sections on medical robotics and endoscopic devices; validation; brain tumor, cortex, vascular, and imaging and analysis; segmentation; cardiac applications; computer-assisted diagnosis; tubular structures; interventions; simulation; modelling; statistical shape modelling; image registration; visualization; and novel imaging techniques.