This is a terrific book. Yes, it's technical, but if you managed to get through moderately advanced High School science courses, or if you hacked college, don't sweat it, you'll get it. Di Pasquale--an M.D.--gives much in-depth, detailed information on the metabolism, physiological effects of, and potential for excercise enhancement of amino acids, proteins, and their effect on body hormones. Di Pasquale knows that the reader wants to apply the information to athletic performance. He talks about both anaerobic and aerobic excercise, but since he is a former powerlifting champion, he zeroes in on anaerobic excercise (e.g., bodybuilding, powerlifting), which is very refreshing. You also get summary detail toward the end of the book that gives sample supplement doses and critical timing of dosing to maximize results. Di Pasquale also weighs in on other non-amino acid supplements that affect anabolism (or purport to) such as Pyruvate, HMB, etc. (There's no info on steroids, so forget about that.) Overall a terrific advance for bodybuilders and worth it if you want to get away from all the hype and zero in on some science. This book is for the thinking bodybuider. Naturals, in particular, have much to gain.