This book constitutes the refereed proceedings of the 15th International Conference on Analytical and Stochastic Modeling Techniques and Applications, ASMTA 2008, held in Nicosia, Cyprus, in June 2008 in conjunction with ECMS 2008, the 22nd European Conference on Modeling and Simulation.The 22 revised full papers presented were carefully reviewed and selected from 55 submissions. The papers are organized in topical sections on traffic modeling, queueing systems, analytical methods and applications, distributions in stochastic modeling, queueing networks, simulation and model checking, as well as wireless networks.