This book constitutes the refereed proceedings of the 5th International Conference on Artificial Immune Systems, ICARIS 2006, held in Oeiras, Portugal in September 2006.
The 34 revised full papers presented were carefully reviewed and selected from 60 submissions. The papers are organized in topical sections on computer simulation of classical immunology, computer simulation of idiotypic network, immunoinformatics conceptual papers, pattern recognition type of application, optimization type of application, control and time-series type of application, danger theory inspired application, and text mining application.