UK-based Coles has been active in the field of pharmaceutical isolation technology for 20 years. Suitable for both experienced and beginning professionals, the second edition of Coles' text reflects significant changes in the acceptance and the understanding of isolation technology in the five years since publication of the first edition. Revised and updated throughout, the text provides descriptions of and comments on new guidelines and standards, and describes technological advances, such as the new breed of sanitizing gas generators. Illustrated with b&w photographs, diagrams, and charts