With an abundance of illustrations, diagrams, and algorithms for a reader-friendly review of critical material, this Sixth Edition is fully updated and revised to clearly update and explore current diagnostic and clinical applications of immunology, as well as strategies for the modulation of immune response and the treatment of hypersensitivity, autoimmune response, and immune deficiency conditions. Organized into four sections that review clinical applications, methodological advances, immunological diseases, and cutting edge interventions, this guide leads readers through state-of-the-sciences technologies and demonstrates their implementation in day-to-day clinical practice.