This book is designed for a computationally intensive graduate course based around a collection of classical unsolved extremal problems for polynomials. These problems, all of which lend themselves to extensive computational exploration, live at the interface of analysis, combinatorics and number theory so the techniques involved are diverse.A main computational tool used is the LLL algorithm for finding small vectors in a lattice. Many exercises and open research problems are included. Indeed one aim of the book is to tempt the able reader into the rich possibilities for research in this area.